April 24, 2017
Earlier in his career, Paul Bolno worked with neuroscientists at drug giant GlaxoSmithKline PLC. Today, as chief executive of Wave Life Sciences Ltd., he is leading the Cambridge biotech’s effort to advance two experimental drugs that could become the first treatments for the progressive brain disorder Huntington’s disease.
April 19, 2017
Alzheimer's Association (April 12, 2017): FDA Approves At-Home Test for an Alzheimer’s Disease Risk Gene: What You Need to Know
Perhaps your grandmother had Alzheimer’s disease; maybe your mom or dad is currently living with the disease. You may be concerned that you are seeing signs of the disease in yourself or a loved one. Whatever the situation, if your family has been touched by Alzheimer’s, it is natural to be curious if a genetic test is valuable in predicting the likelihood of developing the disease.
April 18, 2017
“If only,” wrote an ancient Japanese poet, “when one heard that Old Age was coming one could bolt the door….”
Science is working on it.
Aging is as much about the physical processes of repair and regeneration — and their slow-motion failure — as it is the passage of time. And scientists studying stem cell and regenerative biology are making progress understanding those processes, developing treatments for the many diseases whose risks increase as we get older, while at times seeming to draw close to a broader anti-aging breakthrough.
April 17, 2017
In one of the largest studies of its type, researchers confirm a link between midlife vascular disease and late-life dementia. As reported in the April 11 Journal of the American Medical Association, 50-year-olds with two or more vascular risk factors were almost three times more likely to have amyloid in the brain in their 70s as were those with no signs of cardiovascular disease in middle age. Researchers said that the study, led by Rebecca Gottesman at Johns Hopkins University School of Medicine, Baltimore, was impressive for the number of subjects and its prospective design.
April 12, 2017
North Dakota’s sparse geography has long made it a natural frontier: Pioneers here pushed the boundaries of westward expansion, then agriculture, and recently domestic oil drilling. Now the state finds itself on the leading edge of a new boom that it never would have chosen: Alzheimer’s disease.
April 11, 2017
When scientists began tracking the health of 268 Harvard sophomores in 1938 during the Great Depression, they hoped the longitudinal study would reveal clues to leading healthy and happy lives.
They got more than they wanted.
After following the surviving Crimson men for nearly 80 years as part of the Harvard Study of Adult Development, one of the world’s longest studies of adult life, researchers have collected a cornucopia of data on their physical and mental health.
April 6, 2017
Scientists have puzzled for decades over how our brains convert experiences from short-term memories into stored recollections that can be retrieved years later. Now, MIT researchers say they have made a discovery that provides new insight into the circuitry behind how we remember.
April 4, 2017
Catch it early.
Those are watchwords in the battle against a host of illnesses, from heart disease to cancer to Type 2 diabetes. Early detection gives physicians a chance to minimize damage, to insert a stent and keep blood flowing to the heart, to remove a tumor before one becomes many, to urge crucial lifestyle changes: lose weight, eat better, exercise.
But can the strategy work for Alzheimer’s disease? Scientists are starting to think it might.
April 4, 2017
Worcester Telegram (April 3, 2017): Alzheimer’s Research Shifts to Prevention, With Diet as Latest ‘Darling’
Of the top causes of death in the United States, only No. 6, Alzheimer’s disease, can’t be prevented, cured or slowed. Unlike killers such as heart disease, cancer and stroke, the number of deaths from Alzheimer’s disease is rising rapidly, up 89 percent since 2000, according to the Alzheimer’s Association.
Every 66 seconds someone in the U.S. develops the disease, which now affects more than 5 million Americans.
March 21, 2017
It's Your Health with Lisa Davis interviews Dr. Jonathan Jackson – Instructor in Neurology at Massachusetts General Hospital
Dr. Jonathan Jackson, instructor in Neurology at Massachusetts General Hospital interviewed on the Radio show It's Your Health with Lisa Davis to talk about health disparities in regards to Alzheimer's disease and more about the landmark prevention trial for Alzheimer's disease currently enrolling calling The A4 Study.