Forbes.com (June 21, 2017): One Doctor's Hopeful Plan To Eradicate Alzheimer's

July 3, 2017

“I hope I’m one thing worth not forgetting. Tell me that you’ll never let me go. When I can’t find the words that I’m trying to speak, when I don’t know the face in the mirror I see, when I feel I’m forgotten and lost in this world, won’t you please remember me?”~”Remember Me,” written by Chris Mann and Dr. Rudolph Tanzi along with Laura Mann, Willy Beaman and Dr. Dora Kovacs.

“I believe there is a significant possibility that we will have a solid plan for eradicating Alzheimer’s disease by 2025.”

The statement comes from Dr. Rudolph Tanzi, one of the foremost scientists behind curing the progressive, degenerative brain disease that the Alzheimer’s Association predicts will destroy the memories of some 14 million Americans by 2050.

Not if he can help it. Tanzi said his new drug, developed with colleague Steve Wagner of the University of California San Diego (UCSD) and the National Institutes of Health (NIH) Blueprint Neurotherapeutics Network is getting ready for safety trials. The drug is called a “Gamma Secretase Modulator (GSM),” and Tanzi believes it will be at least a part of the prescription for stopping Alzheimer’s disease pathology from leading to symptoms. He said the GSM is expected to enter clinical safety trials with the National Institutes of Health (NIH) by the end of the year.

Tanzi said he fully expects doctors to be managing Alzheimer’s disease like they do heart disease by 2025, if not sooner.

GQ magazine named Tanzi a “Rock Star of Science.” After all, the neurogeneticist did play keyboards on Aerosmith’s last album and often jams with good friend Joe Perry, co-founder and lead guitarist of Aerosmith. But as Boston’s WBZ-TV reporter Paula Ebben put it, “it’s his work in his lab at Mass General Hospital that has rocked the world of Alzheimer’s research.”

www.forbes.com/sites/robinseatonjefferson/2017/06/21/new-drug-that-could...