5-Year Major Projects (1984 - Present)

Brain Amyloid Accrual in Non-Demented People: Preclinical AD or Brain Resilience

Project Year(s): 
2013 to 2018
Principal Investigator(s): 

M. Teresa Gomez-Isla, MD, PhD

Most Recent/Current Position(s): 

Co-Director, Clinical Core, Massachusetts Alzheimer's Disease Research Center & Co-Director, Massachusetts General Hospital Memory Disorders Unit & Associate Professor of Neurology, Harvard Medical School

Mouse Model of Early Alzheimer's Disease

Project Year(s): 
2013 to 2018
Principal Investigator(s): 

Bradley T. Hyman, MD, PhD

Most Recent/Current Position(s): 

Director, Massachusetts ADRC & John B. Penney, Jr. Professor of Neurology, Harvard Medical School

The Role of Advanced Cerebral Amyloid Angiopathy in Alzheimer's Dementia

Project Year(s): 
2008 to 2013
Principal Investigator(s): 

Anand Viswanathan, MD, PhD

Most Recent/Current Position(s): 

Associate Director, Telestroke Services, Massachusetts General Hospital Hemorrhagic Stroke Research Program & Assistant Professor of Neurology, Harvard Medical School

Tau Alterations in Alzheimer and Related Dementias

Project Year(s): 
2003 to 2008
Principal Investigator(s): 

Bradley T. Hyman, MD, PhD

Most Recent/Current Position(s): 

Director, Massachusetts ADRC & John B. Penney, Jr. Professor of Neurology, Harvard Medical School

Genetic Analysis of Alzheimer's Disease

Project Year(s): 
1997 to 2002
Principal Investigator(s): 

Rudolph E. Tanzi, PhD

Most Recent/Current Position(s): 

Director, Genetics & Aging Research Unit, Mass Gen Institute for Neurodegenerative Disease & Joseph P. and Rose F. Kennedy Professor of Child Neurology and Mental Retardation, Harvard Medical School

Mechanism and Inhibition of Native Amyloid-Beta Aggregation in Cells

Project Year(s): 
1997 to 2002
Principal Investigator(s): 

Dennis J. Selkoe, MD

Most Recent/Current Position(s): 

Co-Director, Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital & Vincent and Stella Coates Professor of Neurologic Diseases, Harvard Medical School

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