Announcements

March 14, 2017

National Institute on Aging and Alzheimer's Association Lead Effort to Update Diagnostic Criteria for Alzheimer' Disease

Scientists at the Alzheimer's Association International Conference on Alzheimer's Disease 2010 (AAICAD 2010) today presented the first draft reports from three workgroups convened by the National Institute on Aging (NIA) and the Alzheimer's Association to update the diagnostic criteria for Alzheimer's disease for the first time in 25 years.

The current criteria for the diagnosis of Alzheimer's were established by a National Institute of Neurological Disorders and Stroke (NINDS)/Alzheimer's Disease and Related Disorders  Association (ADRDA) workgroup in 1984. These criteria were almost universally adopted and have been useful; they have survived intact without modification for more than 25 years. However, experts note, the field has evolved to a great extent since then.

"Important scientific discoveries have been made in Alzheimer's, and there have been significant changes in our knowledge and conception of the disease," said Creigton H. Phelps, PhD, Director of the Alzheimer's Disease Centers Program, Division of Neuroscience, National Institute on Aging at the National Institutes of Health. "The NIA and the Alzheimer's Association, after consultation with the Alzheimer's scientific and medical community, concluded that the diagnostic criteria may need to be revised to incorporate scientific advances...

March 14, 2017

Harvard/MIT Joint Research Grants Program in Basic Neuroscience

A new joint research grants program in the basic neuroscience to support collaborative research in the Harvard and Massachusetts Institute of Technology (MIT) communities has just been announced by the Harvard NeuroDiscovery Center.  Applications covering the spectrum of basic neuroscience research will be considered.

A minimum of two laboratories are invited to apply for a 2-year grant, for a total of $100,000 per year, and preference will be given to teams that have not worked previously together. Award will provide salary support (typically, a post-doctoral fellow or graduate student) and equipment/supplies cost.

The due date for the application is August 27, 2010, and awards are expected to commence in October 2010.

More information regarding the grant program is attached.

http://madrc.mgh.harvard.edu/2010-harvardmit-joint-research-grants-program-basic-neuroscience

March 14, 2017

The Drama of Real-Life Unfolding Inside the Nation's Best Hospitals

Boston Med picks up where the Peabody Award-winning Hopkins left off, going even deeper into the lives of caregivers and the cutting edge medical cases they confront inside the walls of America's top hospitals. In this original eight-hour series, the unforgettable stories of doctors, nurses and patients are adeptly woven to give each hour the pace and intensity of a drama. Whether it's the young resident in crisis doubting that she's good enough to become a Harvard-trained doctor, or the deployed soldier's pregnant wife praying for a miracle surgery to save her baby, Boston Med is sure to touch your heart.

Filmed over four months at Massachusetts General, Brigham and Women's, and Children's Hospital Boston, this powerfully real series breaks new ground in the documentary landscape. Meet the charismatic Hollywood producer before either he or the filmmakers realize that, through a twist of fate, his face will be transplanted onto a Vietnam veteran badly scarred in an accident. The second face transplant performed in this country and the first anywhere to be so extensively filmed, this operation involved two dozen surgeons and up to a hundred additional doctors and nurses. It's a stunning example of both the high caliber medicine and the unprecedented and unique access captured by the filmmakers in Boston Med.

http://www.documentingmedicine.com/boston-med-the-drama-of-real-life-unfolding-inside-the-nations-hospitals/

https://lh3.googleusercontent.com/W5FwGludDkmOcbJJZE_WN_Prz_Cb2EWg0UZDNRq3vrLOMwFGczP5cCcZsQye4CAtYmz2=w1264

March 14, 2017

NIH-Supported Study Looks for Earliest Changes in the Brain That May Lead to Alzheimer's Disease

Volunteers are being sought for a clinical study examining the subtle changes that may take place in the brains of older people many years before overt symptoms of Alzheimer's disease appear. Researchers are looking for people with the very earliest complaints of memory problems that affect their daily activities. The study will follow participants over time, using imaging techniques developed to advance research into changes taking place in the structure and function of the living brain, as well as biomarker measures found in blood and cerebrospinal fluid.

The National Institute on Aging (NIA), part of the National Institutes of Health, and the NIH Office of the Director are funding the $24 million, two-year Alzheimer's Disease Neuroimaging Initiative Grand Opportunity (ADNI-GO) study. Researchers seek to recruit 200 volunteers between the ages of 55 and 90 who may be transitioning from normal cognitive aging to an early stage of amnestic mild cognitive impairment (aMCI), a condition that may progress to Alzheimer's disease. Participants may volunteer at 51 sites across the United States.

 

March 14, 2017

The Structured Interview & Scoring Tool - Massachusetts ADRC (SIST-M)*

A Structured Interview & Scoring Tool (SIST-M)* and an accompanying informant report questionnaire - SIST-M-Informant Report (SIST-M-IR)* - have been developed for use in structuring Clinical Dementia Rating (CDR) interviews with our Center's Longitudinal Cohort research subjects with no or mild cognitive impairment, or mild dementia.

 

The SIST-M* and SIST-M-IR* were developed by Drs. Olivia I. Okereke, Deborah L. Blacker, Marilyn S. Albert and other colleagues. 

REGARDING USE OF THE SIST-M AND SIST-M-IR, CURRENT VERSIONS:

 

The SIST-M and SIST-M-IR (current versions) were developed and validated to enable trained clinicians to obtain Clinical Dementia Rating (CDR) overall ratings and sum-of-boxes scores among persons with no to mild degrees of cognitive impairment, including mild dementia. The SIST-M and SIST-M-IR have not been validated for other purposes. The SIST-M and SIST-M-IR are not intended and are not appropriate for persons with moderate dementia or severe cognitive impairment. For more information about the CDR and its scoring rules, please see the CDR Homepage at http://alzheimer.wustl.edu/cdr.

 

For further information regarding use and/or reproduction, contact Dr. Okereke at ookereke@partners.org and Dr. Anne Ritter (Research Ventures & Licensing, Massachusetts General Hospital) at amritter@partners.org.

March 14, 2017

Research Opportunity for 2010

The Massachusetts ADRC has a unique funding opportunity for a pilot grant project to be funded by May 15, 2010 (pending project approval by the NIA/NIH) that is modelled after its recent Call for Applications for its Neurodegenerative Disease Pilot Study Pilot Program.

Interested applicants are requested to send an email inquiry to Bradley T. Hyman, MD, PhD by April 23, 2010. If invited, a 2-page proposal would be due May 1, 2010.

March 14, 2017

Harvard Medical School William Silen Lifetime Achievement in Mentoring Award: Lewis A. Lipsitz, MD

Congratulations to Dr. Lewis A. Lipsitz, co-director of our Education & Information Transfer Core, for receiving the William Silen LIfetime Achievement in Mentoring Award from the Office for Diversity and Community Partnership at Harvard Medical School.

The 2009-2010 Excellence in Mentoring Awards Ceremony will be held on Tuesday, June 1, 2010 from 4:30pm - 6:00pm.

More information regarding the ceremony is attached.

March 14, 2017

Call for Applications: 2010 Tosteson Postdoctoral Fellowship Awards: Massachusetts Biomedical Research Corporation (MBRC) in Basic and Clinical Research at Massachusetts General Hospital

MD and PhD investigators pursuing either basic or clinical research at the Massachusetts General Hospital are encouraged to apply for the 2010 Tosteson Postdoctoral Fellowship Awards funded by the Massachusetts Biomedical Research Corporation (MBRC).

Each award includes a stipend of $40,000, plus applicable fringe benefits and 15% indirect costs, and are effective on or about September 1, 2010. The application deadline for the fellowship award is 3:00pm on April 22, 2010.

Applicants who had submitted an application to the 2010 MGH ECOR Fund for Medical Discovery should not re-apply for the Tosteson Award.

More information regarding eligibility and application information is attached.

 

March 14, 2017

Research Partnership in Cognitive Aging Boosts Funds For Research Grants: Randy L. Buckner, PhD, Among Awardees

The Research Partnership in Cognitive Aging, a public-private effort to promote the study of brain function with age, will award up to $28 million over five years to 17 research grants to examine the neural and behavioral profiles of healthy cognitive aging and explore interventions that may prevent, reduce or reverse cognitive decline in older people.

The partnership, led by the National Institute on Aging (NIA), part of the National Institutes of Health, and the McKnight Brain Research Foundation (MBRF), is seeking ways to maintain cognitive health - the ability to think, learn and remember - into old age.

The basic research supported by these grants will focus on the molecular, cellular, physiological and behavioral aspects of healthy aging as well as the development and pilot testing of experimental, evidence-based interventions. The pilot studies of behavioral strategies may eventually lead to full-scale, randomized clinical trials.

The partnership is supported by NIA and the MBRF through the Foundation for the National Institutes of Health (FNIH), a nonprofit that seeks funding partners for a broad portfolio of groundbreaking programs and projects in support of biomedical research.

www.health.ufl.edu/brain/news.shtml#RPC

March 14, 2017

Catalunya TV3: Un President Contra L'Alzheimer [A President Against Alzheimer's Disease]

Pasqual Maragall i Mira (born January 13, 1941 in Barcelona) is the 127th President of Generalitat de Catalunya (the government of Catalonia in Spain), and the former (115th) Mayor of Barcelona from 1982 to 1997.

Trained in economics and law, he was active in politics in Barcelona for more than three decades. Among his many achievements, Maragall presided over the organizing committee (COOB' 92) for the 1992 Barcelona Summer Olympics; served as President of the Committee of the Regions of the European Union between 1996-1998, and was appointed doctor honoris causa of the Johns Hopkins University in Baltimore.

On October 20, 2007, Maragall announced that he had been diagnosed with Alzheimer's disease, and established the Pasqual Maragall Foundation for Research on Alzheimer's Disease in April 2008. Maragall was featured with Massachusetts ADRC neurologist E. Teresa Gomez-Isla, MD, PhD, in a TV documentary on the disease in 2008. The program was awarded the Boethringer Journalist Prize in Medicine in 2009.

A related documentary entitled Bicycle, Spoon, Apple was screened at the 58th San Sebastian International Film Festival in September 2010.

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